It is used in potentially dangerous gram-positive infections, including those that cannot be treated with other antimicrobials such as penicillins and cephalosporins. .
Thicosin is useful in treating serious staphylococcal infections in patients who cannot or do not respond to penicillins and cephalosporins, or in patients who have staphylococcal infections that are resistant to other antibiotics. .
The effectiveness of ticoplanin in the following infections has been documented :
Soft tissue and skin infections, urinary tract infections, lower respiratory tract infections, joint and bone infections, sepsis, endocarditis and peritonitis associated with outpatient peritoneal dialysis .
Thicosin may also be used for antimicrobial prevention in orthopedic surgeries that are at risk for gram-positive infections. .